Effects of selected polybrominated diphenyl ether flame retardants on lake trout (Salvelinus namaycush) thymocyte viability, apoptosis, and necrosis
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Abstract
Polybrominated diphenyl ether (PBDE) flame-retardants have been identified as an emergent contaminants issue in many parts of the world. In vitro analyses were conducted to test the hypothesis that selected PBDEs congeners affect viability, apoptosis, and necrosis of thymocytes from laboratory-reared lake trout (Salvelinus namaycush). At current environmental levels (<1 mg/L), effects of the tested PBDEs on thymocytes were negligible. However, at 100 mg/L, major effects were seen for congener brominated diphenyl ether 47 (BDE-47) and minor effects were seen for congener BDE-99.
Publication type | Article |
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Publication Subtype | Journal Article |
Title | Effects of selected polybrominated diphenyl ether flame retardants on lake trout (Salvelinus namaycush) thymocyte viability, apoptosis, and necrosis |
Series title | Environmental Toxicology and Chemistry |
DOI | 10.1897/04-347R.1 |
Volume | 24 |
Issue | 6 |
Year Published | 2005 |
Language | English |
Publisher | Wiley |
Contributing office(s) | Great Lakes Science Center |
Description | 5 p. |
First page | 1518 |
Last page | 1522 |
Online Only (Y/N) | N |
Additional Online Files (Y/N) | N |
Google Analytic Metrics | Metrics page |