| Abstract: | Polybrominated diphenyl ether (PBDE) flame-retardants have been identified as an emergent contaminants issue in many parts of the world. In vitro analyses were conducted to test the hypothesis that selected PBDEs congeners affect viability, apoptosis, and necrosis of thymocytes from laboratory-reared lake trout (Salvelinus namaycush). At current environmental levels (<1 mg/L), effects of the tested PBDEs on thymocytes were negligible. However, at 100 mg/L, major effects were seen for congener brominated diphenyl ether 47 (BDE-47) and minor effects were seen for congener BDE-99. |
| Genre: | Article |
| ProdID: | 1001080 |
| Citation Author: | Birchmeier, Kelly L.; Smith, Kimberly A.; Passino-Reader, Dora R.; Sweet, Leonard I.; Chernyak, Sergei M.; Adams, Jean V.; Omann, Geneva M. |
| Citation Contributing Office: | Great Lakes Science Center |
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| Citation End Page: | 1522 |
| Citation Issue: | 6 |
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| Citation Language: | English |
| Citation Larger Work Title: | Environmental Toxicology and Chemistry |
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| Citation Number Of Pages: | 4 |
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| Citation Phsyical Description: | p. 1518-1522 |
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| Citation Search Results Text: | Effects of selected polybrominated diphenyl ether flame retardants on lake trout (Salvelinus namaycush) thymocyte viability, apoptosis, and necrosis; 2005; Article; Journal; Environmental Toxicology and Chemistry; Birchmeier, Kelly L.; Smith, Kimberly A.; Passino-Reader, Dora R.; Sweet, Leonard I.; Chernyak, Sergei M.; Adams, Jean V.; Omann, Geneva M. |
| Citation Start Page: | 1518 |
| Citation Volume: | 24 |
| Citation Year: | 2005 |
| Type: | citation/reference |
| Text: | Effects of selected polybrominated diphenyl ether flame retardants on lake trout (Salvelinus namaycush) thymocyte viability, apoptosis, and necrosis; 2005; Article; Journal; Environmental Toxicology and Chemistry; Birchmeier, Kelly L.; Smith, Kimberly A.; Passino-Reader, Dora R.; Sweet, Leonard I.; Chernyak, Sergei M.; Adams, Jean V.; Omann, Geneva M. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Sat, 1 Jan 2005 00:00 -0600 |
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