| Abstract: | A liquid chromatographic method is described for analysis of benzocaine (BZ), a proposed fish anesthetic, in rainbow trout plasma, Mean recoveries of BZ from plasma samples fortified at 44-10 100 ng/mL were 96-100%. The method detection limit is 10 ng/mL, and the limit of quantitation is 37 ng/mL. Acetylation of BZ occurs in whole blood after storage at room temperature (i.e., 21 degrees C) for 10 min. However, no acetylation of BZ was detected in plasma samples held at room temperature for 4 h, Mean method precision for plasma samples with incurred BZ residue is similar to that for fortified samples in the same concentration range (relative standard deviations of 0.9 and 1.2%, respectively). |
| Genre: | Article |
| ProdID: | 1002895 |
| Citation Author: | Bernardy, Jeffery A.; Coleman, K. S.; Stehly, G. R.; Gingerich, William H. |
| Citation Contributing Office: | Upper Midwest Environmental Sciences Center |
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| Citation End Page: | 627 |
| Citation Issue: | 3 |
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| Citation Language: | English |
| Citation Larger Work Title: | Journal of AOAC International |
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| Citation Number Of Pages: | 5 |
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| Citation Phsyical Description: | pp. 623-627 |
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| Citation Search Results Text: | Determination of benzocaine in rainbow trout plasma; 1996; Article; Journal; Journal of AOAC International; Bernardy, Jeffery A.; Coleman, K. S.; Stehly, G. R.; Gingerich, William H. |
| Citation Start Page: | 623 |
| Citation Volume: | 79 |
| Citation Year: | 1996 |
| Type: | citation/reference |
| Text: | Determination of benzocaine in rainbow trout plasma; 1996; Article; Journal; Journal of AOAC International; Bernardy, Jeffery A.; Coleman, K. S.; Stehly, G. R.; Gingerich, William H. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Mon, 1 Jan 1996 00:00 -0600 |
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