| Abstract: | A simple method was developed for determining florfenicol concentration in a small volume (250 mul) of plasma from five phylogenetically diverse species of freshwater fish. Florfenicol was isolated from the plasma matrix through C-18 solid-phase extraction and quantified by reversed-phase high-performance liquid chromatography with UV detection. The accuracy (84-104%), precision (%RSDless than or equal to8), and sensitivity (quantitation limit <30 ng/ml) of the method indicate its usefulness for conducting pharmacokinetic studies on a variety of freshwater fish. Published by Elsevier Science B.V. |
| Genre: | Article |
| ProdID: | 1002980 |
| Citation Author: | Vue, C.; Schmidt, L. J.; Stehly, G. R.; Gingerich, W. H. |
| Citation Contributing Office: | Upper Midwest Environmental Sciences Center |
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| Citation End Page: | 117 |
| Citation Issue: | 1 |
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| Citation Language: | English |
| Citation Larger Work Title: | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences |
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| Citation Number Of Pages: | 7 |
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| Citation Phsyical Description: | pp. 111-117 |
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| Citation Publisher: | U.S. Geological Survey |
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| Citation Search Results Text: | Liquid chromatographic determination of florfenicol in the plasma of multiple species of fish; 2002; Article; Journal; Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences; Vue, C.; Schmidt, L. J.; Stehly, G. R.; Gingerich, W. H. |
| Citation Start Page: | 111 |
| Citation Volume: | 780 |
| Citation Year: | 2002 |
| Type: | citation/reference |
| Text: | Liquid chromatographic determination of florfenicol in the plasma of multiple species of fish; 2002; Article; Journal; Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences; Vue, C.; Schmidt, L. J.; Stehly, G. R.; Gingerich, W. H. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Tue, 1 Jan 2002 00:00 -0600 |
| Publisher: | U.S. Geological Survey |
