thumbnail

Disposition of 1-naphthol in the channel catfish (Ictalurus punctatus)

Drug Metabolism and Disposition

By:
and

Links

  • The Publications Warehouse does not have links to digital versions of this publication at this time
  • Download citation as: RIS

Abstract

The pharmacokinetics, tissue distribution, and metabolism of 1-naphthol were examined in the channel catfish (Ictalurus punctatus ). After oral dosing, peak plasma concentrations of 1-naphthol occurred at 1 hr; parent compound made up less than 15% of the total radioactivity, and the bioavailability was 32%. Plasma protein binding was 92% and was independent of concentration. 1-Naphthol and metabolites were rapidly eliminated from the tissues after oral dosing.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Disposition of 1-naphthol in the channel catfish (Ictalurus punctatus)
Series title:
Drug Metabolism and Disposition
Volume
20
Issue:
1
Year Published:
1992
Language:
English
Publisher:
U.S. Food and Drug Administration
Publisher location:
Dauphin Island, AL
Contributing office(s):
Upper Midwest Environmental Sciences Center
Description:
pp. 70-73
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Drug Metabolism and Disposition
First page:
70
Last page:
73