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Metabolism of pentachlorophenol by fish

Xenobiotica

By:
,
DOI: 10.3109/00498258909034678

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Abstract

Interspecies variability in the metabolism of pentachlorophenol (PCP) was investigated by exposing rainbow trout, fathead minnows, sheepshead minnow, firemouth, and goldfish to water-borne super(14)C-PCP for 64 h. The amounts of metabolites in bile and exposure water were species-dependent; all of the metabolites excreted into the water were sulphate conjugates while bile was enriched in glucuronide conjugates. Biliary excretion accounted for less than 30% of the total PCP metabolites. Biliary metabolites alone were a poor indication of the metabolites produced and of the major routes of elimination.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Metabolism of pentachlorophenol by fish
Series title:
Xenobiotica
DOI:
10.3109/00498258909034678
Volume
19
Issue:
1
Year Published:
1989
Language:
English
Publisher:
Great Lakes Environ. Res. Lab., NOAA
Contributing office(s):
Upper Midwest Environmental Sciences Center
Description:
pp. 75-81
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Xenobiotica
First page:
75
Last page:
81
Number of Pages:
7