Metabolism of pentachlorophenol by fish
Xenobiotica
By: G. R. Stehly and W. L. Hayton
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Abstract
Interspecies variability in the metabolism of pentachlorophenol (PCP) was investigated by exposing rainbow trout, fathead minnows, sheepshead minnow, firemouth, and goldfish to water-borne super(14)C-PCP for 64 h. The amounts of metabolites in bile and exposure water were species-dependent; all of the metabolites excreted into the water were sulphate conjugates while bile was enriched in glucuronide conjugates. Biliary excretion accounted for less than 30% of the total PCP metabolites. Biliary metabolites alone were a poor indication of the metabolites produced and of the major routes of elimination.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Metabolism of pentachlorophenol by fish |
| Series title | Xenobiotica |
| DOI | 10.3109/00498258909034678 |
| Volume | 19 |
| Issue | 1 |
| Year Published | 1989 |
| Language | English |
| Publisher | Great Lakes Environ. Res. Lab., NOAA |
| Contributing office(s) | Upper Midwest Environmental Sciences Center |
| Description | pp. 75-81 |
| Larger Work Type | Article |
| Larger Work Subtype | Journal Article |
| Larger Work Title | Xenobiotica |
| First page | 75 |
| Last page | 81 |
| Google Analytic Metrics | Metrics page |