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Efficacy of a type C botulism vaccine in green-winged teal

Journal of Wildlife Diseases

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Abstract

We tested the efficacy of a single dose of Botumink toxoid for protecting wild green-winged teal (Anas crecca) during botulism epizootics caused by Clostridium botulinum type C. We challenged control and immunized ducks with four different doses of type C botulinum toxin to determine the LD50 for this species and to evaluate vaccine protection. Fewer immunized ducks were affected with botulism than control ducks, indicating that a single dose of Botumink toxoid could increase the survival of ducks during epizootics. However, the frequency of immunized ducks with signs of botulism increased with the challenge dose of botulinum toxin. Even at doses of botulinum toxin approximately 2 to 4 green-winged teal LD50, about 50% of the immunized ducks were affected. We believe an improved vaccine or a better delivery system is required to justify immunization of wild birds for experimental survival studies.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Efficacy of a type C botulism vaccine in green-winged teal
Series title:
Journal of Wildlife Diseases
Volume
36
Issue:
3
Year Published:
2000
Language:
English
Contributing office(s):
National Wildlife Health Center
Description:
p. 489-493
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
First page:
489
Last page:
493
Number of Pages:
5