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Modest genetic differentiation among North American populations of Sarcocystic neurona may reflect expansion in its geographic range

Veterinary Parasitology

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Abstract

Sarcocystis neurona is an important cause of neurological disease in horses (equine protozoal myeloencephalitis, EPM) and sea otters in the United States. In addition, EPM-like disease has been diagnosed in several other land and marine mammals. Opossums are its only definitive hosts. Little genetic diversity among isolates of S. neurona from different hosts has been reported. Here, we used 11 microsatellites to characterize S. neurona DNA isolated from natural infections in 22 sea otters (Enhydra lutris) from California and Washington and in 11 raccoons (Procyon lotor) and 1 striped skunk (Mephitis mephitis) from Wisconsin. By jointly analyzing these 34 isolates with 26 isolates previously reported, we determined that geographic barriers may limit S. neurona dispersal and that only a limited subset of possible parasite genotypes may have been introduced to recently established opossum populations. Moreover, our study confirms that diverse intermediate hosts share a common infection source, the opossum (Didelphis virginiana).

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Modest genetic differentiation among North American populations of Sarcocystic neurona may reflect expansion in its geographic range
Series title:
Veterinary Parasitology
Volume
152
Issue:
1-2
Year Published:
2008
Language:
English
Contributing office(s):
National Wildlife Health Center
Description:
p. 8-15
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Veterinary Parasitology
First page:
8
Last page:
15