| Abstract: | Many naturally occurring toxins, as well as pesticides, metals, and other compounds that occur in our environment from anthropogenic activities, stimulate or antagonize neuro-receptors to produce acute and/or chronic toxicities. Recent advances in laboratory instrumentation and the availability of a variety of radiolabeled ligands and type-specific drugs for numerous receptors make it possible to easily screen large numbers of samples and detect changes in sensitivity and density of receptor types and subtypes. A receptor binding assay for examining the chronic dietary toxicity of parathion will be used as a model to describe the methodology. |
| Genre: | Book chapter |
| ProdID: | 5210680 |
| Citation Author: | Jett D.A.; Eldefrawi A.T.; Eldefrawi M.E. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
| Citation Datum: | |
| Citation Day: | |
| Citation Edition: | |
| Citation Editor: | |
| Citation End Page: | 262 |
| Citation Issue: | |
| Citation Keywords: | |
| Citation Language: | English |
| Citation Larger Work Title: | Environmental toxicology and risk assessment, 2nd volume; Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial, Pittsburgh, Pennsylvania, USA, April 26-30, 1992 |
| Citation LatN: | |
| Citation LatS: | |
| Citation LonE: | |
| Citation LonW: | |
| Citation Month: | |
| Citation No Pagination: | |
| Citation Number Of Pages: | |
| Citation Online Only Flag: | |
| Citation Phsyical Description: | xii+730 |
| Citation Projection: | |
| Citation Public Comments: | OCLC: 29694316 |
| Citation Publisher: | American Society for Testing and Materials |
| Citation Series: | ASTM Special Technical Publication |
| Citation Series Code: | |
| Citation Series Number: | 1216 |
| Citation Search Results Text: | A receptor binding assay applied to monitoring the neurotoxicity of parathion to Peromyscus after oral exposure; 1993; Book chapter; 1216; Book; Environmental toxicology and risk assessment, 2nd volume; Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial, Pittsburgh, Pennsylvania, USA, April 26-30, 1992; Jett D.A.; Eldefrawi A.T.; Eldefrawi M.E. |
| Citation Start Page: | 253 |
| Citation Volume: | |
| Citation Year: | 1993 |
| Type: | citation/reference |
| Text: | A receptor binding assay applied to monitoring the neurotoxicity of parathion to Peromyscus after oral exposure; 1993; Book chapter; 1216; Book; Environmental toxicology and risk assessment, 2nd volume; Symposium on Environmental Toxicology and Risk Assessment: Aquatic, Plant, and Terrestrial, Pittsburgh, Pennsylvania, USA, April 26-30, 1992; Jett D.A.; Eldefrawi A.T.; Eldefrawi M.E. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DIGITAL OBJECT IDENTIFIER): | http://dx.doi.org/10.1520/STP13159S |
| Date Other: | Tue, 9 Jun 2009 00:00 -0500 |
| Publisher: | American Society for Testing and Materials |
