Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors

Ludke, J.L.; Hill, E.F.; Dieter, M.P.

Abstract:

Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20% indicated exposure, and inhibition greater than 50% was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion or carbofuran had brain ChE activities below 55% of normal; although individuals could survive with brain ChE activity lower than 50%. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed.

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Article

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5221348

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Ludke, J.L.; Hill, E.F.; Dieter, M.P.

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Patuxent Wildlife Research Center

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English

Citation Larger Work Title:

Archives of Environmental Contamination and Toxicology

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1-21

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1717_Ludke.pdf

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Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors; 1975; Article; Journal; Archives of Environmental Contamination and Toxicology; Ludke, J.L.; Hill, E.F.; Dieter, M.P.