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Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors

Archives of Environmental Contamination and Toxicology

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Abstract

Patterns of mortality and inhibition of brain and plasma ChE in birds treated with ChE inhibitors were studied in an attempt to determine the validity of using ChE activity as a monitoring and diagnostic technique. Analysis of brain ChE activity proved to be reliable for diagnosing and monitoring effects of selected ChE inhibitors in birds. Brain ChE inhibition exceeding 20% indicated exposure, and inhibition greater than 50% was sufficient for diagnosing cause of death. Individuals that died from dietary exposure to parathion or carbofuran had brain ChE activities below 55% of normal; although individuals could survive with brain ChE activity lower than 50%. Problems associated with collection, storage, and analysis of tissues for ChE activity are discussed.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Cholinesterase (ChE) response and related mortality among birds fed ChE inhibitors
Series title:
Archives of Environmental Contamination and Toxicology
Volume
3
Issue:
1
Year Published:
1975
Language:
English
Contributing office(s):
Patuxent Wildlife Research Center
Description:
1-21
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
First page:
1
Last page:
21
Number of Pages:
21