| Abstract: | Mallard drakes (Anas platyrhynchos) fed 1, 5, or 25 ppm lead nitrate were bled and sacrificed at 3-wk intervals. No mortality occurred, and the pathologic lesions usually associated with lead poisoning were not found. Changes in hematocrit and hemoglobin concentration did not occur. After 3-wk ducks fed 25 ppm lead exhibited a 40% inhibition of blood delta-aminolevulinic acid dehydratase activity that persisted through 12 wk exposure. After 12 wk treatment similar enzyme inhibition was present in the ducks fed 5 ppm lead. At 3 wk there was a small accumulation of lead (less than 1 ppm) in the liver and kidneys of ducks fed 25ppm lead; no further increases occurred throughout the exposure. No significant accumulation of lead occurred the the tibiae or wing bones. Groups of ducks fed 5 and 25 ppm diets for 12 wk were placed on clean feed and examined through a 12 wk posttreatment period. After 3 wk on clean diet delta-aminolevulinic acid dehydratase activity and lead concentrations in the blood had returned to pretreatment levels. Even though lead concentrations in the blood, soft organs and bone were low, a highly significant negative correlation between blood lead and blood enzyme activity was obtained. This enzyme bioassay should provide a sensitive and precise estimate for monitoring lead in the blood for waterflow. |
| Genre: | Article |
| ProdID: | 5221378 |
| Citation Author: | Finley, M.T.; Dieter, M.P.; Locke, L.N. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
| Citation Datum: | |
| Citation Day: | |
| Citation Edition: | |
| Citation Editor: | |
| Citation End Page: | 937 |
| Citation Issue: | 6 |
| Citation Keywords: | |
| Citation Language: | English |
| Citation Larger Work Title: | Journal of Toxicology and Environmental Health |
| Citation LatN: | |
| Citation LatS: | |
| Citation LonE: | |
| Citation LonW: | |
| Citation Month: | |
| Citation No Pagination: | |
| Citation Number Of Pages: | 9 |
| Citation Online Only Flag: | |
| Citation Phsyical Description: | 929-937 |
| Citation Projection: | |
| Citation Public Comments: | |
| Citation Publisher: | Taylor and Francis |
| Citation Series: | |
| Citation Series Code: | |
| Citation Series Number: | |
| Citation Search Results Text: | Sublethal effects of chronic lead ingestion in mallard ducks; 1976; Article; Journal; Journal of Toxicology and Environmental Health; Finley, M.T.; Dieter, M.P.; Locke, L.N. |
| Citation Start Page: | 929 |
| Citation Volume: | 1 |
| Citation Year: | 1976 |
| Type: | citation/reference |
| Text: | Sublethal effects of chronic lead ingestion in mallard ducks; 1976; Article; Journal; Journal of Toxicology and Environmental Health; Finley, M.T.; Dieter, M.P.; Locke, L.N. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DIGITAL OBJECT IDENTIFIER): | http://dx.doi.org/10.1080/15287397609529395 |
| Date Other: | Wed, 16 Jun 2010 00:00 -0500 |
| Publisher: | Taylor and Francis |
