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Lead accumulation and depression of delta-aminolevulinic acid dehydratase (ALAD) in young birds fed automotive waste oil

Archives of Environmental Contamination and Toxicology

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Abstract

The effects of a 3-week dietary exposure to automotive waste crankcase oil (WCO) were examined in 1-week-old mallard (Anas platyrhynchos) ducklings and pheasant (Phasianus colchicus) chicks. Treatment groups consisted of birds exposed to 0.5, 1.5, or 4.5% WCO, to 4.5% clean crankcase oil (CCO), or untreated controls. In both species, red blood cell ALAD activity was significantly inhibited after one week by 50 to 60% in the 0.5% WCO group and by 85 to 90% in the 4.5% WCO group due to the presence of lead. Growth, hematocrit, and hemoglobin were not significantly affected at the end of three weeks. Plasma aspartate aminotransferase (AST) activity was higher in mallards after three weeks of ingesting either 4.5% WCO or 4.5% CCO, suggesting an oil-related effect due to components other than lead. Treatment had no effect on plasma concentration of uric acid, glucose, triglycerides, total protein, or cholesterol. Lead analysis showed the WCO to contain 4,200 ppm Pb and the CCO to contain 2 ppm. Tissues of mallards were examined for accumulation of lead and the order of accumulation at the end of three weeks was kidney > liver > blood ~ brain.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Lead accumulation and depression of delta-aminolevulinic acid dehydratase (ALAD) in young birds fed automotive waste oil
Series title:
Archives of Environmental Contamination and Toxicology
Volume
12
Issue:
1
Year Published:
1983
Language:
English
Contributing office(s):
Patuxent Wildlife Research Center
Description:
31-35
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Archives of Environmental Contamination and Toxicology
First page:
31
Last page:
35
Number of Pages:
5