| Abstract: | Oral intubation of 50 and 100 mg/kg acephate inhibited brain acetylcholinesterase (AChE) activity by 45% and 56%, and reduced basal luteinizing hormone (LH) concentration by 29% and 25% after 4 h in white-footed mice (Peromyscus leucopus noveboracensis). Dietary exposure to 25, 100, and 400 ppm acephate for 5 days substantially inhibited brain AChE activity, but did not affect plasma LH concentration. These preliminary findings suggest that acute exposure to organophosphorus insecticides may affect LH secretion and possibly reproductive function. |
| Genre: | Article |
| ProdID: | 5222013 |
| Citation Author: | Rattner, B.A.; Michael, S.D. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
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| Citation End Page: | 69 |
| Citation Issue: | 1 |
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| Citation Language: | English |
| Citation Larger Work Title: | Toxicology Letters |
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| Citation Number Of Pages: | 5 |
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| Citation Phsyical Description: | 65-69 |
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| Citation Search Results Text: | Organophosphorus insecticide induced decrease in plasma luteinizing hormone concentration in white-footed mice; 1985; Article; Journal; Toxicology Letters; Rattner, B.A.; Michael, S.D. |
| Citation Start Page: | 65 |
| Citation Volume: | 24 |
| Citation Year: | 1985 |
| Type: | citation/reference |
| Text: | Organophosphorus insecticide induced decrease in plasma luteinizing hormone concentration in white-footed mice; 1985; Article; Journal; Toxicology Letters; Rattner, B.A.; Michael, S.D. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DOCUMENT): | http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCR-478C5WM-HH&_user=696292&_coverDate=01%2F31%2F1985&_rdoc=12&_fmt=high&_orig=browse&_srch=doc-info(%23toc%235177%231985%23999759998%23366207%23FLP%23display%23Volume)&_cdi=5177&_sort=d&_docanchor=&_ct=20&_acct=C000038819&_version=1&_urlVersion=0&_userid=696292&md5=58137affb9f0b1a2b7b0de0881c3ccf4 |
| Date Other: | Wed, 16 Jun 2010 12:18 -0500 |
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