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Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail

Environmental Toxicology and Chemistry

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and

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Abstract

Young Japanese quail (Coturnix japonica) were administered NaF for 16 d either in their diet or by esophageal intubation. Based on the total fluoride ion (Emg F-) intake over the l6-d experimental period, fluoride administered by intubation was at least six times more toxic than that fed in the diet. Dietary concentrations of 1,000 ppm F- (Emg F- for 16 d = approx. 144) produced no mortality, whereas intubated doses produced 73% or greater mortality in all groups administered 54 mg F- /kg/d or more (Emg F- for 16 d _ approx. 23 mg). GraphIc companson of the regression of log F- ppm in femurs/mg F- intake showed that fluoride levels in the femurs of quail administered fluoride by intubation were higher than in those administered fluoride in the diet.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail
Series title:
Environmental Toxicology and Chemistry
Volume
7
Issue:
10
Year Published:
1988
Language:
English
Contributing office(s):
Patuxent Wildlife Research Center
Description:
841-845
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Environmental Toxicology and Chemistry
First page:
841
Last page:
845
Number of Pages:
5