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Developmental toxicity of lead-contaminated sediment in Canada geese (Branta canadensis)

Journal of Toxicology and Environmental Health, Part A: Current Issues

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DOI: 10.1080/009841000156916

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Abstract

Sediment ingestion has recently been identified as an important exposure route for toxicants in waterfowl. The effects of lead-contaminated sediment from the Coeur d'Alene River Basin (CDARB) in Idaho on posthatching development of Canada geese (Branta canadensis) were examined for 6 wk. Day-old goslings received either untreated control diet, clean sediment (48%) supplemented control diet, or CDARB sediment (3449 mug/g lead) supplemented diets at 12%, 24%, or 48%. The 12% CDARB diet resulted in a geometric mean blood lead concentration of 0.68 ppm (ww), with over 90% depression of red blood cell ALAD activity and over fourfold elevation of free erythrocyte protoporphyrin concentration. The 24% CDARB diet resulted in blood lead of 1.61 ppm with decreased hematocrit, hemoglobin, and plasma protein in addition to the effects just described. The 48% CDARB diet resulted in blood lead of 2.52 ppm with 22% mortality, decreased growth, and elevated plasma lactate dehydrogenase-L (LDH-L) activity. In this group the liver lead concentration was 6.57 ppm (ww), with twofold increases in hepatic lipid peroxidation (thiobarbituric acid-reactive substances, TBARS) and in reduced glutathione concentration; associated effects included elevated glutathione reductase activity but lower protein-bound thiols concentration and glucose-6-phosphate dehydrogenase (G-6-PDH) activity. The kidney lead concentration in this group was 14.93 ppm with subacute renal tubular nephrosis in one of the surviving goslings. Three other geese in this treatment group exhibited calcified areas of marrow, and one of these displayed severe chronic fibrosing pancreatitis. Lead from CDARB sediment accumulated less readily in gosling blood and tissues than reported in ducklings but at given concentrations was generally more toxic to goslings. Many of these effects were similar to those reported in wild geese and mallards within the Coeur d'Alene River Basin.

Geospatial Extents

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Developmental toxicity of lead-contaminated sediment in Canada geese (Branta canadensis)
Series title:
Journal of Toxicology and Environmental Health, Part A: Current Issues
DOI:
10.1080/009841000156916
Volume
59
Issue:
4
Year Published:
2000
Language:
English
Publisher:
Taylor and Francis
Contributing office(s):
Patuxent Wildlife Research Center
Description:
18 p.
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Journal of Toxicology and Environmental Health, Part A: Current Issues
First page:
235
Last page:
252
Country:
United States
State:
Idaho
Other Geospatial:
Coeur D'alene River Basin
Online Only (Y/N):
N
Additional Online Files(Y/N):
N