| Abstract: | To evaluate cytochrome P-450 related parameters as biomarkers of pollutant exposure, rates of arylhydrocarbon hydroxylase (AHH), ethoxyresorufin-O-deethylase (EROD), benzyloxyROD (BROD), pentoxyROD (PROD) and ethoxycoumarinOD (ECOD) were studied in 10-day-old BCNHs (Nycticorax nycticorax). Nestlings were collected from Chincoteague National Wildlife Refuge, VA (‘controls‘) and from polluted sites including. Cat Island, Green Bay, WI, and Bair and West Marin Islands, San Francisco Bay, CA. Livers were frozen (-70.C) for monooxygenase assays and SDS-PAGE. Microsomal AHH and BROD activities were greater (P2 standard deviations from the control mean (induced up to 3-fold). EROD, PROD and ECOD did not differ among sites. Absence of an EROD response with AHH and BROD induction in BCNHs is different than responses in other species. The association of pollutant burdens with P-450 parameters is being studied. These biomarkers may serve as a rapid screen of exposure in a national contaminant biomonitoring program and other assessment activities. |
| Genre: | Article |
| ProdID: | 5223997 |
| Citation Author: | Rattner, B.A.; Melancon, M.J.; Custer, T.W.; Hothem, R.L.; King, K.A.; LeCaptain, L.J.; Spann, J.W. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
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| Citation Language: | English |
| Citation Larger Work Title: | Society of Environmental Toxicology and Chemistry, annual meeting abstract book |
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| Citation Phsyical Description: | 103 (abstract no. 420) |
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| Citation Search Results Text: | Monooxygenase activity of black-crowned night-heron (BCNH) nestlings in Virginia, the Great Lakes and San Francisco Bay; 1990; Article; Journal; Society of Environmental Toxicology and Chemistry, annual meeting abstract book; Rattner, B.A.; Melancon, M.J.; Custer, T.W.; Hothem, R.L.; King, K.A.; LeCaptain, L.J.; Spann, J.W. |
| Citation Start Page: | 103 (abstr |
| Citation Volume: | 11 |
| Citation Year: | 1990 |
| Type: | citation/reference |
| Text: | Monooxygenase activity of black-crowned night-heron (BCNH) nestlings in Virginia, the Great Lakes and San Francisco Bay; 1990; Article; Journal; Society of Environmental Toxicology and Chemistry, annual meeting abstract book; Rattner, B.A.; Melancon, M.J.; Custer, T.W.; Hothem, R.L.; King, K.A.; LeCaptain, L.J.; Spann, J.W. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Wed, 16 Jun 2010 12:19 -0500 |
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