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Differences in oxidative stress between young Canada geese and mallards exposed to lead-contaminated sediment

Journal of Toxicology and Environmental Health, Part A

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Abstract

Lead (Pb) exposure causes an increase in tissue lipid peroxides and variation in glutathione (GSH) concentration, which can be related to peroxidative damage of cell membranes in Pb poisoned animals. Species and individual variation in sensitivity to Pb poisoning among animals may be due to differential resistance to oxidative stress. We compared the effects of oxidative stress caused by Pb exposure (1.7, 414 and 828 ig/g of diet) for the first six weeks in growing young of two species of waterfowl, Canada geese (Branta canadensis) and mallards (Anas platyrhynchos), with the first species being possibly more sensitive to Pb poisoning based on previous field and laboratory observations. Blood and liver Pb concentrations increased more in mallards than in geese; this may be explained on the basis of body weight, being 3.2 times higher in geese, and hepatic metabolism where GSH-S-transferase activity is 2.9 fold higher in geese and presumably has a role in the binding of Pb to GSH and subsequent biliary excretion. In contrast, mallards showed higher hepatic levels of GSH and activities of GSH peroxidase (GPX) and GSH reductase (GR). Although both species showed an increase in hepatic GSH concentration with Pb exposure, the increase of lipid peroxidation with Pb exposure was more significant in geese. Within treatment groups, hepatic GSH concentrations were inversely related to liver Pb concentration in both species, which may correspond to the role of GSH in Pb excretion. Hepatic GSH was also inversely related to hepatic lipid peroxidation, but only in mallards and in agreement with the differences observed in GPX and GR activities. The lower resistance to lipid peroxidation of Canada geese may explain why birds of this species found dead in the field by Pb shot ingestion often have a lower number of shot in the gizzard and lower liver Pb concentrations than mallards.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Differences in oxidative stress between young Canada geese and mallards exposed to lead-contaminated sediment
Series title:
Journal of Toxicology and Environmental Health, Part A
Volume
64
Issue:
7
Year Published:
2001
Language:
English
Contributing office(s):
Patuxent Wildlife Research Center
Description:
531-545
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Journal of Toxicology and Environmental Health, Part A
First page:
531
Last page:
545
Number of Pages:
15