| Abstract: | Associations between contaminant exposure and liver and skin tumor prevalence were evaluated in brown bullheads (Ameiurus nebulosus) from the tidal Potomac River watershed. Thirty bullheads (>260 mm) were collected from (1) Quantico embayment, near a Superfund site which released organochlorine contaminants; (2) Neabsco Creek, a tributary with petroleum inputs from runoff and marinas; and (3) Anacostia River (spring and fall), an urban tributary designated as a Chesapeake Bay Region of Concern, contaminated with PCBs, PAHs, and organochlorine pesticides. Fish were collected from the Tuckahoe River, as a reference. Cytochrome P450 activity, bile PAH metabolites, and muscle organochlorine pesticide/PCB concentrations were measured in randomly-selected individuals and sediment contaminants were analyzed. We found statistically significant differences in liver tumor prevalences: Anacostia (spring)-50%, Anacostia (fall)-60%, Neabsco-17%, Quantico-7%, Tuckahoe-10%. Skin tumor prevalences were significantly different: Anacostia (spring)-37%, Anacostia (fall)-10%, Neabsco-3%, Quantico-3%, Tuckahoe-0%. Tumor prevalence in Anacostia bullheads warrants concern and was similar to those at highly contaminated sites in the Great Lakes. There was evidence of higher PAH exposure in Anacostia fish but a cause-effect linkage cannot be established. Fish tumor surveys, with histopathological examination of internal and external organs, are recommended for monitoring the status of Regions of Concern. |
| Genre: | Article |
| ProdID: | 5224170 |
| Citation Author: | Pinkney, A.E.; Harshbarger, J.C.; May, E.B.; Melancon, M.J. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
| Citation Datum: | |
| Citation Day: | |
| Citation Edition: | |
| Citation Editor: | |
| Citation End Page: | |
| Citation Issue: | |
| Citation Keywords: | |
| Citation Language: | English |
| Citation Larger Work Title: | Society of Environmental Toxicology and Chemistry, Annual Meeting Abstract Book |
| Citation LatN: | |
| Citation LatS: | |
| Citation LonE: | |
| Citation LonW: | |
| Citation Month: | |
| Citation No Pagination: | |
| Citation Number Of Pages: | |
| Citation Online Only Flag: | |
| Citation Phsyical Description: | |
| Citation Projection: | |
| Citation Public Comments: | Environmental Sciences in the 21st Century: Paradigms, opportunities, and challenges, Nashville, Tennessee, November 12-16. |
| Citation Publisher: | |
| Citation Series: | |
| Citation Series Code: | |
| Citation Series Number: | |
| Citation Search Results Text: | Tumor prevalence and biomarkers in brown bullheads (Ameiurus nebulosus) from the tidal Potomac River watershed [poster]; 2000; Article; Journal; Society of Environmental Toxicology and Chemistry, annual meeting abstract book ; Pinkney, A.E.; Harshbarger, J.C.; May, E.B.; Melancon, M.J. |
| Citation Start Page: | 165 (abstr |
| Citation Volume: | 21 |
| Citation Year: | 2000 |
| Type: | citation/reference |
| Text: | Tumor prevalence and biomarkers in brown bullheads (Ameiurus nebulosus) from the tidal Potomac River watershed [poster]; 2000; Article; Journal; Society of Environmental Toxicology and Chemistry, annual meeting abstract book ; Pinkney, A.E.; Harshbarger, J.C.; May, E.B.; Melancon, M.J. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Wed, 16 Jun 2010 12:13 -0500 |
| Publisher: | |
