| Abstract: | Golden Bear Oil (GB-1111; legal trade name for GB-1313) is a petroleum distillate used in the United States and other countries as a mosquito larvicide. As part of an evaluation of the potential effects of GB-1111 on birds, fertile eggs of mallards (Anas platyrhynchos) and bobwhite (Colinus virginianus) were incubated in the laboratory, and treated on day 4 of incubation with external applications equivalent to either 0, 1/3, 1, 3 or 10 times the maximum rate (X) of 47 l/ha (5 gal/A) of field application of GB-1111. Hatching success was significantly reduced in mallards treated at 3 and 10 times the maximum field application, with a calculated approximate LD50 of 1.9 times the maximum field application. Most mortality occurred within a week of treatment. Hepatic P450-associated monooxygenase activity (ethoxyresorufin-O-dealkylase; EROD) was negatively related to dose. In the 3X group there was a significant increase in the concentration of hepatic reduced glutathione (GSH) but a decrease in proteinbound thiols (PBSH). Hatching success of bobwhite was marginally reduced at the highest level of treatment (10X). Other effects at this level in bobwhite included a significant increase in incidence of abnormal embryos or hatchlings, lower body and liver weights, and a twofold increase in hepatic microsomal EROD activity in hatchlings. The recommended maximum rate of field application of GB-1111 is unlikely to impair the survival or development of bobwhite embryos but is potentially toxic to mallard embryos under conditions of larvicide drift or spray overlap. |
| Genre: | Article |
| ProdID: | 5224293 |
| Citation Author: | Hoffman, D.J.; Albers, P.H.; Melancon, M.J.; Miles, A.K. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
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| Citation End Page: | 358 |
| Citation Issue: | 3 |
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| Citation Language: | English |
| Citation Larger Work Title: | Environmental Pollution |
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| Citation Number Of Pages: | 6 |
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| Citation Phsyical Description: | 353-358 |
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| Citation Public Comments: | 6134_Hoffman.pdf |
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| Citation Search Results Text: | Effects of the mosquito larvicide GB-1111 on bird eggs; 2004; Article; Journal; Environmental Pollution; Hoffman, D.J.; Albers, P.H.; Melancon, M.J.; Miles, A.K. |
| Citation Start Page: | 353 |
| Citation Volume: | 127 |
| Citation Year: | 2004 |
| Type: | citation/reference |
| Text: | Effects of the mosquito larvicide GB-1111 on bird eggs; 2004; Article; Journal; Environmental Pollution; Hoffman, D.J.; Albers, P.H.; Melancon, M.J.; Miles, A.K. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DOCUMENT): | http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6VB5-49SWC6J-3&_user=696292&_coverDate=02%2F29%2F2004&_rdoc=7&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%235917%232004%23998729996%23470891%23FLA%23display%23Volume)&_cdi=5917&_sort=d&_docanchor=&_ct=18&_acct=C000038819&_version=1&_urlVersion=0&_userid=696292&md5=36ab8502817cc7e60f4bec1e22343977 |
| Date Other: | Wed, 16 Jun 2010 12:18 -0500 |
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