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Host mating system and the spread of a disease-resistant allele in a population

Theoretical Population Biology

By:
, , , and
DOI: 10.1016/j.tpb.2008.07.001

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Abstract

The model presented here modifies a susceptible-infected (SI) host-pathogen model to determine the influence of mating system on the outcome of a host-pathogen interaction. Both deterministic and stochastic (individual-based) versions of the model were used. This model considers the potential consequences of varying mating systems on the rate of spread of both the pathogen and resistance alleles within the population. We assumed that a single allele for disease resistance was sufficient to confer complete resistance in an individual, and that both homozygote and heterozygote resistant individuals had the same mean birth and death rates. When disease invaded a population with only an initial small fraction of resistant genes, inbreeding (selfing) tended to increase the probability that the disease would soon be eliminated from a small population rather than become endemic, while outcrossing greatly increased the probability that the population would become extinct due to the disease.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Host mating system and the spread of a disease-resistant allele in a population
Series title:
Theoretical Population Biology
DOI:
10.1016/j.tpb.2008.07.001
Volume
74
Issue:
2
Year Published:
2008
Language:
English
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
Theoretical Population Biology
First page:
191
Last page:
198