| Abstract: | Diphenhydramine hydrochloride (DH; Benadryl TM, an over-the-counter antihistamine) and erythromycin thiocyanate (ET; a commonly used macrolide antibiotic) are pharmaceutical compounds whose chronic toxicity to Daphnia magna had not been characterized. Continuous exposure to DH concentrations about 5 times greater than the maximum reported environmental concentration of 0.023 lg/L for 21 days or to ET concentrations about 40 times the maximum reported environmental concentration of 6 (mu or u)g/L for 21 days did not significantly impact D. magna survival and production. In this study the no observable effect concentration for DH was 0.12 (mu or u)g/L and for ET was 248 (mu or u)g/L. |
| Genre: | Article |
| ProdID: | 70003552 |
| Citation Author: | Meinertz, J. R.; Schreier, T. M.; Bernardy, J. A.; Franz, J. L. |
| Citation Contributing Office: | Upper Midwest Environmental Sciences Center |
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| Citation End Page: | 451 |
| Citation Issue: | 5 |
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| Citation Language: | English |
| Citation Larger Work Title: | Bulletin of Environmental Contamination and Toxicology |
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| Citation Phsyical Description: | 5 p. |
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| Citation Publisher: | Springer |
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| Citation Search Results Text: | Chronic toxicity of diphenhydramine hydrochloride and erythromycin thiocyanate to Daphnia, Daphnia magna, in a continuous exposure test system; 2010; Article; Journal; Bulletin of Environmental Contamination and Toxicology; Meinertz, J. R.; Schreier, T. M.; Bernardy, J. A.; Franz, J. L. |
| Citation Start Page: | 447 |
| Citation Volume: | 85 |
| Citation Year: | 2010 |
| Type: | citation/reference |
| Text: | Chronic toxicity of diphenhydramine hydrochloride and erythromycin thiocyanate to Daphnia, Daphnia magna, in a continuous exposure test system; 2010; Article; Journal; Bulletin of Environmental Contamination and Toxicology; Meinertz, J. R.; Schreier, T. M.; Bernardy, J. A.; Franz, J. L. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| URL (DOCUMENT): | http://www.springerlink.com/content/a4w27671l0150nv0/ |
| Date Other: | Wed, 22 Jun 2011 13:50 -0500 |
| Publisher: | Springer |
