| Abstract: | Most strains of Clostridium botulinum type C, after having lost their capacity to produce their dominant toxin (C1) as a result of being "cured" of their prophages, continue to produce C2, a trypsin-activable toxin reported by other investigators. While of relatively low toxicity when administered perorally to the adult mallard duck (Anas platyrhynchos), it was highly toxic when given parenterally. By the intravenous route, for example, it was more than 1,000 times as toxic as C1 toxin by the same route, when compared on the basis of mouse intraperitoneal toxicity. The cause of death in every instance was massive pulmonary edema and hemorrhage rather than the respiratory paralysis that occurs in C1 intoxication. |
| Genre: | Article |
| ProdID: | 70006667 |
| Citation Author: | Jensen, W. I.; Duncan, R. M. |
| Citation Contributing Office: | National Wildlife Health Center |
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| Citation End Page: | 86 |
| Citation Issue: | 2 |
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| Citation Language: | English |
| Citation Larger Work Title: | Japanese Journal of Medical Science and Biology |
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| Citation Number Of Pages: | 6 |
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| Citation Phsyical Description: | 6 p. |
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| Citation Public Comments: | Abstract has subscript/superscript to be fixed |
| Citation Publisher: | National Institute of Health |
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| Citation Search Results Text: | The susceptibility of the mallard duck (Anas platyrhynchos) to Clostridium botulinum C2 toxin; 1980; Article; Journal; Japanese Journal of Medical Science and Biology; Jensen, W. I.; Duncan, R. M. |
| Citation Start Page: | 81 |
| Citation Volume: | 33 |
| Citation Year: | 1980 |
| Type: | citation/reference |
| Text: | The susceptibility of the mallard duck (Anas platyrhynchos) to Clostridium botulinum C2 toxin; 1980; Article; Journal; Japanese Journal of Medical Science and Biology; Jensen, W. I.; Duncan, R. M. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Sun, 1 Jan 2012 13:43 -0600 |
| Publisher: | National Institute of Health |
