Residues of the lampricides 3-trifluoromethyl-4-nitrophenol and niclosamide in muscle tissue of rainbow trout

Journal of Agricultural and Food Chemistry
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Abstract

Rainbow trout (Oncorhyncus mykiss) were exposed to the 14C- labeled lampricide 3-trifluoromethyl-4-nitrophenol (TFM) (2.1 mg/L) or niclosamide (0.055 mg/L) in an aerated static water bath for 24 h. Fish were sacrificed immediately after exposure. Subsamples of skin-on muscle tissue were analyzed for residues of the lampricides. The primary residues in muscle tissue from fish exposed to TFM were parent TFM (1.08 ?? 0.82 nmol/g) and TFM-glucuronide (0.44 ?? 0.24 nmol/g). Muscle tissue from fish exposed to niclosamide contained niclosamide (1.42 ?? 0.51 nmol/g), niclosamide-glucuronide (0.0644 ?? 0.0276 nmol/g), and a metabolite not previously reported, niclosamide sulfate ester (1.12 ?? 0.33 nmol/g).
Publication type Article
Publication Subtype Journal Article
Title Residues of the lampricides 3-trifluoromethyl-4-nitrophenol and niclosamide in muscle tissue of rainbow trout
Series title Journal of Agricultural and Food Chemistry
DOI 10.1021/jf050156o
Volume 53
Issue 13
Year Published 2005
Language English
Larger Work Type Article
Larger Work Subtype Journal Article
Larger Work Title Journal of Agricultural and Food Chemistry
First page 5342
Last page 5346
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