Interleukin-6 and tumor necrosis factor-alpha values in elk neonates
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Abstract
Serological indicators of general condition would be helpful for monitoring or assessing ungulate wildlife. Toward that end, we report the 1st reference values for 2 cytokines, interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-??), in neonatal elk (Cervus elaphus). We obtained blood samples from 140 calves ??? 6 days old in Yellowstone National Park during summer 2003-2005. TL-6 values ranged from 0 to 1.21 pg/ml with a median of 0.03 pg/ml. TNF-?? values ranged from 0 to 225.43 pg/ml with a median of 1.85 pg/ml. IL-6 and TNF-?? concentrations were not significant predictors of elk calf survival through 21 days. Development of ungulate-based IL-6 and TNF-?? assays that provide greater sensitivity than cross-reacting human-based assays could be helpful in monitoring ungulate condition and health status comparisons among herds. Such information could provide indirect assessments of range quality or environmental influences among herds.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Interleukin-6 and tumor necrosis factor-alpha values in elk neonates |
| Series title | Journal of Mammalogy |
| DOI | 10.1644/06-MAMM-A-182.1 |
| Volume | 88 |
| Issue | 2 |
| Year Published | 2007 |
| Language | English |
| Contributing office(s) | Northern Prairie Wildlife Research Center |
| Description | 6 p. |
| Larger Work Type | Article |
| Larger Work Subtype | Journal Article |
| Larger Work Title | Journal of Mammalogy |
| First page | 421 |
| Last page | 426 |
| Google Analytic Metrics | Metrics page |