| Abstract: | The epidemic of severe acute respiratory syndrome (SARS) was caused by a newly emerged coronavirus (SARS-CoV). Bats of several species in southern People‘s Republic of China harbor SARS-like CoVs and may be reservoir hosts for them. To determine whether bats in North America also harbor coronaviruses, we used reverse transcription-PCR to detect coronavirus RNA in bats. We found coronavirus RNA in 6 of 28 fecal specimens from bats of 2 of 7 species tested. The prevalence of viral RNA shedding was high: 17% in Eptesicus fuscus and 50% in Myotis occultus. Sequence analysis of a 440-bp amplicon in gene 1b showed that these Rocky Mountain bat coronaviruses formed 3 clusters in phylogenetic group 1 that were distinct from group 1 coronaviruses of Asian bats. Because of the potential for bat coronaviruses to cause disease in humans and animals, further surveillance and characterization of bat coronaviruses in North America are needed. |
| Genre: | Article |
| ProdID: | 70030870 |
| Citation Author: | Dominguez, S. R.; O'Shea, T. J.; Oko, L. M.; Holmes, K. V. |
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| Citation End Page: | 1300 |
| Citation Issue: | 9 |
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| Citation Language: | English |
| Citation Larger Work Title: | Emerging Infectious Diseases |
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| Citation Number Of Pages: | 6 |
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| Citation Search Results Text: | Detection of group 1 coronaviruses in bats in North America; 2007; Article; Journal; Emerging Infectious Diseases; Dominguez, S. R.; O‘Shea, T. J.; Oko, L. M.; Holmes, K. V. |
| Citation Start Page: | 1295 |
| Citation Volume: | 13 |
| Citation Year: | 2007 |
| Type: | citation/reference |
| Text: | Detection of group 1 coronaviruses in bats in North America; 2007; Article; Journal; Emerging Infectious Diseases; Dominguez, S. R.; O‘Shea, T. J.; Oko, L. M.; Holmes, K. V. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Mon, 1 Jan 2007 00:00 -0600 |
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