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Gene-expression signatures of Atlantic salmon's plastic life cycle

General and Comparative Endocrinology

By:
, ,
DOI: 10.1016/j.ygcen.2009.04.021

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Abstract

How genomic expression differs as a function of life history variation is largely unknown. Atlantic salmon exhibits extreme alternative life histories. We defined the gene-expression signatures of wild-caught salmon at two different life stages by comparing the brain expression profiles of mature sneaker males and immature males, and early migrants and late migrants. In addition to life-stage-specific signatures, we discovered a surprisingly large gene set that was differentially regulated-at similar magnitudes, yet in opposite direction-in both life history transitions. We suggest that this co-variation is not a consequence of many independent cellular and molecular switches in the same direction but rather represents the molecular equivalent of a physiological shift orchestrated by one or very few master regulators. ?? 2009 Elsevier Inc. All rights reserved.

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Gene-expression signatures of Atlantic salmon's plastic life cycle
Series title:
General and Comparative Endocrinology
DOI:
10.1016/j.ygcen.2009.04.021
Volume
163
Issue:
3
Year Published:
2009
Language:
English
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Larger Work Title:
General and Comparative Endocrinology
First page:
278
Last page:
284
Number of Pages:
7