thumbnail

High seroprevalence of antibodies to avian influenza viruses among wild waterfowl in Alaska: implications for surveillance

PLoS ONE

By:
, , , , , ,
DOI: 10.1371/journal.pone.0058308

Links

Abstract

We examined seroprevalence (presence of detectable antibodies in serum) for avian influenza viruses (AIV) among 4,485 birds, from 11 species of wild waterfowl in Alaska (1998–2010), sampled during breeding/molting periods. Seroprevalence varied among species (highest in eiders (Somateria and Polysticta species), and emperor geese (Chen canagica)), ages (adults higher than juveniles), across geographic locations (highest in the Arctic and Alaska Peninsula) and among years in tundra swans (Cygnus columbianus). All seroprevalence rates in excess of 60% were found in marine-dependent species. Seroprevalence was much higher than AIV infection based on rRT-PCR or virus isolation alone. Because pre-existing AIV antibodies can infer some protection against highly pathogenic AIV (HPAI H5N1), our results imply that some wild waterfowl in Alaska could be protected from lethal HPAIV infections. Seroprevalence should be considered in deciphering patterns of exposure, differential infection, and rates of AIV transmission. Our results suggest surveillance programs include species and populations with high AIV seroprevalences, in addition to those with high infection rates. Serologic testing, including examination of serotype-specific antibodies throughout the annual cycle, would help to better assess spatial and temporal patterns of AIV transmission and overall disease dynamics.

Geospatial Extents

Additional Publication Details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
High seroprevalence of antibodies to avian influenza viruses among wild waterfowl in Alaska: implications for surveillance
Series title:
PLoS ONE
DOI:
10.1371/journal.pone.0058308
Volume
8
Issue:
3
Year Published:
2013
Language:
English
Publisher:
Public Library of Science
Publisher location:
San Francisco, CA
Contributing office(s):
National Wildlife Health Center
Description:
e58308; 7 p.
Larger Work Type:
Article
Larger Work Subtype:
Journal Article
Country:
United States
State:
Alaska