Toxicogenomics in regulatory ecotoxicology

Environmental Science & Technology
By: , and 

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Abstract

Recently, we have witnessed an explosion of different genomic approaches that, through a combination of advanced biological, instrumental, and bioinformatic techniques, can yield a previously unparalleled amount of data concerning the molecular and biochemical status of organisms. Fueled partially by large, well-publicized efforts such as the Human Genome Project, genomic research has become a rapidly growing topical area in multiple biological disciplines. Since 1999, when the term “toxicogenomics” was coined to describe the application of genomics to toxicology (1), a rapid increase in publications on the topic has occurred (Figure 1). The potential utility of toxicogenomics in toxicological research and regulatory activities has been the subject of scientific discussions and, as with any new technology, has evoked a wide range of opinion (2–6).

Publication type Article
Publication Subtype Journal Article
Title Toxicogenomics in regulatory ecotoxicology
Series title Environmental Science & Technology
DOI 10.1021/es0630184
Volume 40
Issue 13
Year Published 2006
Language English
Publisher American Chemical Society
Contributing office(s) Columbia Environmental Research Center
Description 11 p.
First page 4055
Last page 4065
Online Only (Y/N) N
Additional Online Files (Y/N) N
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