We developed a blended (or hybrid) interactive course—Managing for a Changing Climate—that provides a holistic view of climate change. The course results from communication with university students and natural and cultural resource managers as well as the need for educational efforts aimed at the public, legislators, and decision-makers. Content includes the components of the physical climate system, natural climate variability, anthropogenic drivers of climate change, climate models and projections, climate assessments, energy economics, environmental policy, vulnerabilities to climate hazards, impacts of climate change, and decision-making related to climate adaptation and mitigation efforts. To convey most of the content, the course-development team created over 50 short videos (3–10 min each) in partnership with experts from a variety of academic, government, and industry institutions. The blended course has been offered as an upper-division, undergraduate course in the Department of Geography and Environmental Sustainability and School of Meteorology (four times) and College of International Studies (in Italy, once) at the University of Oklahoma with over 100 total students. The course has also been presented online-only at no cost to the participants in four fall semesters with over 1,000 total registrations. Videos created for this course are freely available on the YouTube page of the South Central Climate Adaptation Science Center. This course and its associated materials comprise high-quality, formal climate training and education that can be adapted to other formal and informal education settings beyond the walls of the university.