| Abstract: | As in mammals and fish, birds respond to many environmental contaminants with induction of hepatic cytochromes P450. In order to monitor cytchromes P450 in specific avian species, for assessing the status of that species or the habitat it utilizes, it is necessary to have background information on the appropriate assay conditions and the responsiveness of cytochrome P450 induction in that species. Assay of four monooxygenases which give resorufin as product using a fluorescence microwell plate scanner has proven to be an effective approach. Information is provided on the incubation conditions and baseline activity for twenty avian species at ages ranging from pipping embryo to adult. Induction responsiveness is presented for sixteen of them. This information can serve as a guide for those who wish to utilize cytochrome P450 as a biomarker for contaminant exposure and effect to aid in selection of appropriate species, age, and monooxygenase assay(s). |
| Genre: | Book chapter |
| ProdID: | 5210783 |
| Citation Author: | Melancon, M.J. |
| Citation Contributing Office: | Patuxent Wildlife Research Center |
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| Citation Editor: | Bengston, David A.; Henshel, Diane S. (editors) |
| Citation End Page: | 108 |
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| Citation Language: | English |
| Citation Larger Work Title: | Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment |
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| Citation Phsyical Description: | xiii, 476 p. |
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| Citation Public Comments: | OCLC: 36115842. Contains papers presented at the 5th Symposium on Environmental Toxicology and Risk Assessment held on 3-5 April, 1995, Denver, Colorado. |
| Citation Publisher: | American Society for Testing and Materials |
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| Citation Series Number: | 1306 |
| Citation Search Results Text: | Development of cytochromes P450 in avian species as a biomarker for environmental contaminant exposure and effect: Procedures and baseline values; 1996; Book chapter; 1306; Book; Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment; Melancon, M.J. |
| Citation Start Page: | 95 |
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| Citation Year: | 1996 |
| Type: | citation/reference |
| Text: | Development of cytochromes P450 in avian species as a biomarker for environmental contaminant exposure and effect: Procedures and baseline values; 1996; Book chapter; 1306; Book; Environmental Toxicology and Risk Assessment: Biomarkers and Risk Assessment; Melancon, M.J. |
| URL (THUMBNAIL): | http://pubs.er.usgs.gov/thumbnails/outside_thumb.jpg |
| Date Other: | Tue, 9 Jun 2009 00:00 -0500 |
| Publisher: | American Society for Testing and Materials |
