Water-resources data were collected to describe the hydrologic conditions at four research stations in the Piedmont and Blue Ridge Physiographic Provinces of North Carolina. Data collected by the U.S. Geological Survey and the North Carolina Department of Environment and Natural Resources, Division of Water Quality, from September 2000 through September 2004 are presented in this report. The locations and periods of data collection are as follows: the Lake Wheeler Road research station (Raleigh) from April 2001 to September 2004, the Langtree Peninsula research station (Mooresville) from September 2000 to September 2004, the Upper Piedmont research station (Reidsville) from March 2002 to September 2004, and the Bent Creek research station (Asheville) from July 2002 to September 2004. Data presented in this report include well-construction characteristics for 110 wells, periodic ground-water-level measurements for 96 wells, borehole geophysical logs for 23 wells, hourly ground-water-level measurements for 12 wells, continuous-stage measurements for 2 streams, continuous water-quality measurements for 8 wells and 2 streams, periodic water-quality samples for 57 wells and 6 stream sites, slug-test results for 38 wells, and shallow ground-water-flow maps. In addition, the geology and hydrogeology at each site are summarized.