Residue dynamics of quinaldine and TFM in rainbow trout
General Pharmacology
By: J. B. Hunn and J. L. Allen
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Abstract
Study of the residue dynamics of 2-methylquinoline (quinaldine) and 3-trifluoromethyl-4-nitrophenol (TFM) in rainbow trout yielded the following findings:
1. Uptake and distribution of TFM by trout was influenced by the biotransformation of the lipidsoluble free phenol. No such effect was observed with quinaldine.
2. Disappearance of quinaldine and TFM from gallbladder bile was slower than from plasma or muscle during 24 hr of withdrawal in fresh water.
3. The concentration of TFM conjugate may exceed that of free TFM in bile by a factor of 103.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Residue dynamics of quinaldine and TFM in rainbow trout |
| Series title | General Pharmacology |
| DOI | 10.1016/0306-3623(75)90004-X |
| Volume | 6 |
| Issue | 1 |
| Year Published | 1975 |
| Language | English |
| Publisher | Elsevier |
| Contributing office(s) | Upper Midwest Environmental Sciences Center |
| Description | 4 p. |
| First page | 15 |
| Last page | 18 |
| Google Analytic Metrics | Metrics page |