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Sulfonamide toxicity in brook trout

Transactions of the American Fisheries Society

By:
, , and
DOI:10.1577/1548-8659(1954)84[155:STIBT]2.0.CO;2

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Abstract

Sterility was observed in female brook trout that were treated with sulfamerazine at frequent intervals for 2 years to control endemic furunculosis. Feeding sulfamerazine for a period of 8 months caused massive kidney damage similar to that observed in humans who develop allergies to “sulfa” drugs. Kidney damage of the type observed would probably cause renal insufficiency which would handicap any physiological function including reproduction. Feeding sulfonamides for periods up to 13 weeks did not produce kidney damage.

Additional publication details

Publication type:
Article
Publication Subtype:
Journal Article
Title:
Sulfonamide toxicity in brook trout
Series title:
Transactions of the American Fisheries Society
DOI:
10.1577/1548-8659(1954)84[155:STIBT]2.0.CO;2
Volume:
84
Issue:
1
Year Published:
1954
Language:
English
Publisher:
American Fisheries Society
Contributing office(s):
Western Fisheries Research Center, Leetown Science Center
Description:
6 p.
First page:
155
Last page:
160
Online Only (Y/N):
N
Additional Online Files (Y/N):
N