Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail

Environmental Toxicology and Chemistry
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Abstract

Young Japanese quail (Coturnix japonica) were administered NaF for 16 d either in their diet or by esophageal intubation. Based on the total fluoride ion (Emg F-) intake over the l6-d experimental period, fluoride administered by intubation was at least six times more toxic than that fed in the diet. Dietary concentrations of 1,000 ppm F- (Emg F- for 16 d = approx. 144) produced no mortality, whereas intubated doses produced 73% or greater mortality in all groups administered 54 mg F- /kg/d or more (Emg F- for 16 d _ approx. 23 mg). GraphIc companson of the regression of log F- ppm in femurs/mg F- intake showed that fluoride levels in the femurs of quail administered fluoride by intubation were higher than in those administered fluoride in the diet.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Influence of the method of fluoride administration on toxicity and fluoride concentrations in Japanese quail
Series title Environmental Toxicology and Chemistry
Volume 7
Issue 10
Year Published 1988
Language English
Contributing office(s) Patuxent Wildlife Research Center
Description 841-845
Larger Work Type Article
Larger Work Subtype Journal Article
Larger Work Title Environmental Toxicology and Chemistry
First page 841
Last page 845