Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury

Environmental Toxicology and Chemistry
By: , and 

Links

Abstract

Methylmercury (MeHg) is a potent neurotoxicant and endocrine disruptor that accumulates in aquatic systems. Previous studies have shown suppression of hormone levels in both male and female fish, suggesting effects on gonadotropin regulation in the brain. The gene expression profile in adult female zebrafish whole brain induced by acute (96 h) MeHg exposure was investigated. Fish were exposed by injection to 0 or 0.5(mu or u)g MeHg/g. Gene expression changes in the brain were examined using a 22,000-feature zebrafish microarray. At a significance level of p

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Gene expression changes in female zebrafish (Danio rerio) brain in response to acute exposure to methylmercury
Series title Environmental Toxicology and Chemistry
DOI 10.1002/etc.409
Volume 30
Issue 2
Year Published 2011
Language English
Publisher SETAC
Publisher location Brussels, Belgium
Contributing office(s) Columbia Environmental Research Center, Contaminant Biology Program
Description 8 p.
First page 301
Last page 308