Use of Rhodamine B as a biomarker for oral plague vaccination of prairie dogs
Journal of Wildlife Diseases
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Abstract
Oral vaccination against Yersinia pestis could provide a feasible approach for controlling plague in prairie dogs (Cynomys spp.) for conservation and public health purposes. Biomarkers are useful in wildlife vaccination programs to demonstrate exposure to vaccine baits. Rhodamine B (RB) was tested as a potential biomarker for oral plague vaccination because it allows nonlethal sampling of animals through hair, blood, and feces. We found that RB is an appropriate marker for bait uptake studies of C. ludovicianus) when used at concentrations <0.5% of bait mass dosed to deliver >10 mg RB per kg target animal mass. Whiskers with follicles provided the best sample for RB detection.
| Publication type | Article |
|---|---|
| Publication Subtype | Journal Article |
| Title | Use of Rhodamine B as a biomarker for oral plague vaccination of prairie dogs |
| Series title | Journal of Wildlife Diseases |
| DOI | 10.7589/0090-3558-47.3.765 |
| Volume | 47 |
| Issue | 3 |
| Year Published | 2011 |
| Language | English |
| Publisher | Wildlife Disease Association |
| Publisher location | Lawrence, KS |
| Contributing office(s) | National Wildlife Health Center |
| Description | 4 p. |
| First page | 765 |
| Last page | 768 |
| Online Only (Y/N) | N |
| Additional Online Files (Y/N) | N |
| Google Analytic Metrics | Metrics page |