Migratory flyway and geographical distance are barriers to the gene flow of influenza virus among North American birds

Ecology Letters
By: , and 

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Abstract

Despite the importance of migratory birds in the ecology and evolution of avian influenza virus (AIV), there is a lack of information on the patterns of AIV spread at the intra-continental scale. We applied a variety of statistical phylogeographic techniques to a plethora of viral genome sequence data to determine the strength, pattern and determinants of gene flow in AIV sampled from wild birds in North America. These analyses revealed a clear isolation-by-distance of AIV among sampling localities. In addition, we show that phylogeographic models incorporating information on the avian flyway of sampling proved a better fit to the observed sequence data than those specifying homogeneous or random rates of gene flow among localities. In sum, these data strongly suggest that the intra-continental spread of AIV by migratory birds is subject to major ecological barriers, including spatial distance and avian flyway.

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Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Migratory flyway and geographical distance are barriers to the gene flow of influenza virus among North American birds
Series title Ecology Letters
DOI 10.1111/j.1461-0248.2011.01703.x
Volume 15
Issue 1
Year Published 2012
Language English
Publisher Blackwell Publishing
Publisher location Malden, MA
Contributing office(s) National Wildlife Health Center
Description 10 p.
First page 24
Last page 33
Country United States
State California, Oregon, Washington
Online Only (Y/N) N
Additional Online Files (Y/N) N