The 87Sr/86Sr ratios have been determined in 22 volcanic rocks from Oregon and Washington. The emphasis of the study was on andesites and dacites, but several basalts were included. Most of the samples have a very limited range in strontium isotopic composition and all fall within variations previously defined for oceanic basalts. There are no systematic differences between lavas erupted through the pre-Cenozoic basement and those erupted in the Columbia River Embayment. It is concluded that the role played by crustal rocks in the generation of these andesites and dacites is minor or nonexistent, but assimiliation of crustal material may have been a factor for some of the basalts of the Columbia River Group. ?? 1970.