This paper is included in the Special Publication entitled 'Dating and duration of fluid flow and fluid-rock interaction', edited by J. Parnell. The Viburnum Trend is a world-class Mississippi Valley-type (MVT) lead-zinc ore deposit in platform carbonates of the Upper Cambrian Bonneterre Dolomite in the midcontinent of the USA. Palaeomagnetic methods have been used to analyse 233 specimens from early octahedral (nine sites) and late-stage cubic (13 sites) galena ore from four mines along the c. 70 km north-south length of the Trend. The characteristic remanence is carried by single to pseudo-single domain pyrrhotite and magnetite. This is the first MVT deposit in which pyrrhotite is shown to be a remanence carrier and present in galena crystals. The remanence directions define an Early Permian mean age of 273 ?? 10 Ma for the ore-stage mineralization, a maximum duration for the mineralization event of 12 Ma, and a time difference of 5 Ma between the early octahedral and late cubic galena ore stages. The Early Permian age for the ore is consistent with models of ore genesis that invoke fluid flow from the Ouachita orogen during Ouachitan orogenesis.