Acidic deposition is the transfer of strong acids and acid-forming substances from the atmosphere to the surface of the Earth. The composition of acidic deposition includes ions, gases, and particles derived from the following: gaseous emissions of sulfur dioxide (SO₂), nitrogen oxides (NO_x), ammonia (NH₃), and particulate emissions of acidifying and neutralizing compounds. Over the past quarter century of study, acidic deposition has emerged as a critical environmental stress that affects forested landscapes and aquatic ecosystems in North America, Europe, and Asia. This complex problem is an example of a new class of environmental issues that are multiregional in scale and are not amenable to simple resolution by policymakers. Acidic deposition can originate from transboundary air pollution and can affect large geographic areas. It is highly variable across space and time, links air pollution to diverse terrestrial and aquatic ecosystems, and alters the interactions of many elements (e.g., sulfur [S], nitrogen [N], hydrogen ion [H⁺], calcium [Ca²⁺], magnesium [Mg²⁺], and aluminum [Al]). It also contributes directly and indirectly to biological stress and to the degradation of ecosystems. Despite the complexity of the effects of acidic deposition, North American and European management actions directed toward the recovery of damaged natural resources have resulted in recent decreases in both emissions and deposition of acidic S compounds. Accordingly, acidic deposition presents an instructive case study for coordinating science and policy efforts aimed at resolving large-scale environmental problems.