Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus

Diseases of Aquatic Organisms
By: , and 



Brown bullhead Ameiurus nebulosus is used as indicator species for contaminant effects at areas of concern (AOC) in the Great Lakes and other areas. One of the beneficial use impairments at numerous AOC is 'fish tumors and other deformities'. An impairment occurs when the prevalence of fish tumors and other deformities exceeds those at unimpacted or control sites or when survey data confirm the presence of neoplastic or preneoplastic liver lesions in bullhead or white sucker Catostomus commersonii. Numerous surveys have been conducted over the years assessing neoplasia in these fishes, both liver and skin tumors. However, a major problem in comparing the results has been a lack of consistent criteria for evaluating histological changes in bullhead livers. As individual AOC develop and implement remedial action plans, realistic and attainable delisting targets need to be specified. For this to occur and be consistent from site to site there must be standardization of the criteria being used to evaluate specific impairments. In this report, specific diagnostic criteria are provided for both non-neoplastic and neoplastic proliferative hepatocellular and biliary lesions. These criteria should assist fish pathologists in describing and categorizing proliferative liver lesions from brown bullhead. ?? Inter-Research 2006.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Diagnostic criteria for proliferative hepatic lesions in brown bullhead Ameiurus nebulosus
Series title Diseases of Aquatic Organisms
Volume 72
Issue 1
Year Published 2006
Language English
Publisher Inter-Research
Description p.19-30
Larger Work Type Article
Larger Work Subtype Journal Article
Larger Work Title Diseases of Aquatic Organisms
First page 19
Last page 30
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