Aim: To understand drivers of vegetation type distribution and sensitivity to climate change. Location: Interior Alaska. Methods: A logistic regression model was developed that predicts the potential equilibrium distribution of four major vegetation types: tundra, deciduous forest, black spruce forest and white spruce forest based on elevation, aspect, slope, drainage type, fire interval, average growing season temperature and total growing season precipitation. The model was run in three consecutive steps. The hierarchical logistic regression model was used to evaluate how scenarios of changes in temperature, precipitation and fire interval may influence the distribution of the four major vegetation types found in this region. Results: At the first step, tundra was distinguished from forest, which was mostly driven by elevation, precipitation and south to north aspect. At the second step, forest was separated into deciduous and spruce forest, a distinction that was primarily driven by fire interval and elevation. At the third step, the identification of black vs. white spruce was driven mainly by fire interval and elevation. The model was verified for Interior Alaska, the region used to develop the model, where it predicted vegetation distribution among the steps with an accuracy of 60-83%. When the model was independently validated for north-west Canada, it predicted vegetation distribution among the steps with an accuracy of 53-85%. Black spruce remains the dominant vegetation type under all scenarios, potentially expanding most under warming coupled with increasing fire interval. White spruce is clearly limited by moisture once average growing season temperatures exceeded a critical limit (+2 ??C). Deciduous forests expand their range the most when any two of the following scenarios are combined: decreasing fire interval, warming and increasing precipitation. Tundra can be replaced by forest under warming but expands under precipitation increase. Main conclusion: The model analyses agree with current knowledge of the responses of vegetation types to climate change and provide further insight into drivers of vegetation change. ?? 2005 Blackwell Publishing Ltd.