Two endangered Microtus pennsylvanicus dukecampbelli (Florida Salt Marsh Vole) were captured at a new location, in February of 2009, at Lower Suwannee National Wildlife Refuge. Since the species discovery in 1979, only 43 Florida Salt Marsh Voles (hereafter FSM Vole) have been captured. Outside of the type locality, this is only the second documented location for the FSM Vole. Given the difficulty in trapping this species and the lack of information about its life history, its discovery in a new location lends itself to the possibility that it is more widespread in the Central Florida Gulf Coast than previously thought. Although much of the salt marsh in the area is in public ownership, a good deal of it has already been altered by logging or development and is threatened by global climate change. More research is needed to adequately protect and manage the habitat for the FSM Vole. A study of FSM Vole coastal salt marsh habitat could also serve as a valuable monitoring tool for subtle changes in salt marsh habitats as global climate change progresses.