Gene-expression signatures of Atlantic salmon's plastic life cycle

General and Comparative Endocrinology
By: , and 

Links

Abstract

How genomic expression differs as a function of life history variation is largely unknown. Atlantic salmon exhibits extreme alternative life histories. We defined the gene-expression signatures of wild-caught salmon at two different life stages by comparing the brain expression profiles of mature sneaker males and immature males, and early migrants and late migrants. In addition to life-stage-specific signatures, we discovered a surprisingly large gene set that was differentially regulated-at similar magnitudes, yet in opposite direction-in both life history transitions. We suggest that this co-variation is not a consequence of many independent cellular and molecular switches in the same direction but rather represents the molecular equivalent of a physiological shift orchestrated by one or very few master regulators. ?? 2009 Elsevier Inc. All rights reserved.
Publication type Article
Publication Subtype Journal Article
Title Gene-expression signatures of Atlantic salmon's plastic life cycle
Series title General and Comparative Endocrinology
DOI 10.1016/j.ygcen.2009.04.021
Volume 163
Issue 3
Year Published 2009
Language English
Larger Work Type Article
Larger Work Subtype Journal Article
Larger Work Title General and Comparative Endocrinology
First page 278
Last page 284
Google Analytic Metrics Metrics page
Additional publication details