TanA: a fluorogenic probe for thiaminase activity

Analytical Methods
By: , and 



A fluorogenic thiamine analogue is presented as a fluorescent probe for thiaminase activity. The emission of the fluorophore is quenched by photoinduced electron transfer (PET) to the N-substituted pyridinium portion of the probe. Action of the enzyme releases the free pyridine group causing a substantial increase in fluorescence.
Publication type Article
Publication Subtype Journal Article
Title TanA: a fluorogenic probe for thiaminase activity
Series title Analytical Methods
DOI 10.1039/C2AY26047F
Volume 5
Issue 2
Year Published 2013
Language English
Publisher RSC Publishing
Contributing office(s) Columbia Environmental Research Center
Description 3 p.
First page 446
Last page 448
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