Interspecies transmission and limited persistence of low pathogenic avian influenza genomes among Alaska dabbling ducks

Infection, Genetics and Evolution
By: , and 

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Abstract

The reassortment and geographic distribution of low pathogenic avian influenza (LPAI) virus genes are well documented, but little is known about the persistence of intact LPAI genomes among species and locations. To examine persistence of entire LPAI genome constellations in Alaska, we calculated the genetic identities among 161 full-genome LPAI viruses isolated across 4 years from five species of duck: northern pintail (Anas acuta), mallard (Anas platyrhynchos), American green-winged teal (Anas crecca), northern shoveler (Anas clypeata) and American wigeon (Anas americana). Based on pairwise genetic distance, highly similar LPAI genomes (>99% identity) were observed within and between species and across a range of geographic distances (up to and >1000 km), but most often between isolates collected 0–10 km apart. Highly similar viruses were detected between years, suggesting inter-annual persistence, but these were rare in our data set with the majority occurring within 0–9 days of sampling. These results identify LPAI transmission pathways in the context of species, space and time, an initial perspective into the extent of regional virus distribution and persistence, and insight into why no completely Eurasian genomes have ever been detected in Alaska. Such information will be useful in forecasting the movement of foreign-origin avian influenza strains should they be introduced to North America.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Interspecies transmission and limited persistence of low pathogenic avian influenza genomes among Alaska dabbling ducks
Series title Infection, Genetics and Evolution
DOI 10.1016/j.meegid.2011.09.011
Volume 11
Issue 8
Year Published 2011
Language English
Publisher Elsevier
Contributing office(s) Alaska Science Center Biology WTEB
Description 7 p.
First page 2004
Last page 2010
Country United States
State Alaska
Online Only (Y/N) N
Additional Online Files (Y/N) N