Accounting for rate variation among lineages in comparative demographic analyses

Evolution
By: , and 

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Abstract

Genetic analyses of contemporary populations can be used to estimate the demographic histories of species within an ecological community. Comparison of these demographic histories can shed light on community responses to past climatic events. However, species experience different rates of molecular evolution, and this presents a major obstacle to comparative demographic analyses. We address this problem by using a Bayesian relaxed-clock method to estimate the relative evolutionary rates of 22 small mammal taxa distributed across northwestern North America. We found that estimates of the relative molecular substitution rate for each taxon were consistent across the range of sampling schemes that we compared. Using three different reference rates, we rescaled the relative rates so that they could be used to estimate absolute evolutionary timescales. Accounting for rate variation among taxa led to temporal shifts in our skyline-plot estimates of demographic history, highlighting both uniform and idiosyncratic evolutionary responses to directional climate trends for distinct ecological subsets of the small mammal community. Our approach can be used in evolutionary analyses of populations from multiple species, including comparative demographic studies.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Accounting for rate variation among lineages in comparative demographic analyses
Series title Evolution
DOI 10.1111/evo.12469
Volume 68
Issue 9
Year Published 2014
Language English
Publisher Wiley-Blackwell Publishing Ltd.
Contributing office(s) Alaska Science Center Biology WTEB
Description 12 p.
First page 2689
Last page 2700
Online Only (Y/N) N
Additional Online Files (Y/N) N