In Response: Biological arguments for selecting effect sizes in ecotoxicological testing—A governmental perspective

Environmental Toxicology and Chemistry
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Abstract

Criticisms of the uses of the no-observed-effect concentration (NOEC) and the lowest-observed-effect concentration (LOEC) and more generally the entire null hypothesis statistical testing scheme are hardly new or unique to the field of ecotoxicology [1-4]. Among the criticisms of NOECs and LOECs is that statistically similar LOECs (in terms of p value) can represent drastically different levels of effect. For instance, my colleagues and I found that a battery of chronic toxicity tests with different species and endpoints yielded LOECs with minimum detectable differences ranging from 3% to 48% reductions from controls [5].

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title In Response: Biological arguments for selecting effect sizes in ecotoxicological testing—A governmental perspective
Series title Environmental Toxicology and Chemistry
DOI 10.1002/etc.3108
Volume 34
Issue 11
Year Published 2015
Language English
Publisher John Wiley and Sonc, Inc.
Contributing office(s) Idaho Water Science Center
Description 3 p.
First page 2440
Last page 2442
Online Only (Y/N) N
Additional Online Files (Y/N) N