Effect of feeding and of DDT on the activity of hepatic glucose 6- phosphate dehydrogenase in two salmonids

Journal of the Fisheries Research Board of Canada
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Abstract

The specific activity of liver glucose 6-phosphate dehydrogenase in yearling rainbow trout remained unchanged when the fish were starved for periods as long as 8 weeks and when starved animals were fed diets of various compositions. Injection of insulin concurrently with refeeding also failed to alter the specific activity of the enzyme in trout. The absence of a dietary or insulin influence on the teleost enzyme system is to be contrasted with studies in mammals in which the activity of hepatic glucose 6-P dehydrogenase was markedly stimulated after refeeding starved animals or injection of insulin.Ingestion of the pesticide DDT by juvenile coho salmon or adult rainbow trout also had no effect on the specific activity of liver glucose 6-P dehydrogenase and DDT failed to inhibit the rainbow trout enzyme in vitro. These results also differ considerably from those found in higher animals.These results suggest that the glucose 6-P dehydrogenase enzyme in teleosts may be under a different type of regulatory control from that found in mammals.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Effect of feeding and of DDT on the activity of hepatic glucose 6- phosphate dehydrogenase in two salmonids
Series title Journal of the Fisheries Research Board of Canada
DOI 10.1139/f69-302
Volume 26
Issue 12
Year Published 1969
Language English
Publisher NRC Research Press
Contributing office(s) Columbia Environmental Research Center
Description 8 p.
First page 3209
Last page 3216
Online Only (Y/N) N
Additional Online Files (Y/N) N