Ceroid in fish

The American Journal of Pathology
By:  and 



Since the original description of ceroid in rats, many papers have appeared on the etiology and characteristics of this pigment. It was first seen as a yellow, granular pigment in hematoxylin and eosin sections of the cirrhotic livers of choline deficient rats. The pigment was more fully characterized by Endicott and Lillie, and additional stainging reactions were summarized recently by Lillie. The pigment is sudanophilic in paraffin sections, acid-fast, basophilic, isotropic, iron negative, and highly resistant to solution in water, alcohol, fat solvents, and dilute aqueous acids and alkalis. It is stained by Mallory's hemofuscin stain and Weigert's myelin stain. It reduces osmium tetraoxide and diamine silver carbonate but not ferric ferricyanide. The Gmelin reactions for bile pigments is negative. It has a greenish yellow fluorescence at 3650-3660 Å. It is Schiff positive with or without antecedent diastase digestion after performic or periodic acid oxidation.

Additional publication details

Publication type Article
Publication Subtype Journal Article
Title Ceroid in fish
Series title The American Journal of Pathology
Volume 32
Issue 3
Year Published 1956
Language English
Publisher American Association of Pathologists and Bacteriologists
Description 13 p.
First page 591
Last page 603
Online Only (Y/N) N
Additional Online Files (Y/N) N